Nomograms from 44647 Oxygen Saturations from Neonates Screened for Congenital Heart Disease in Northeast Brazil
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|Document Type:Original Article|
|Carolina Paim Gomes de Freitas1 1, Felipe Alves Mourato 2, Cícera Rocha dos Santos 3, Renata Grigorio Silva Gomes 4, Cláudio Teixeira Regis 5, Juliana Sousa Soares Araújo 6, Fernanda Cruz de Lira Albuquerque 7, José Luiz de Lima filho2 8, Sandra S Mattos 9,|
|Felipe Alves Mourato , Círculo do Coração de Pernambuco & Laboratório de Imunopatologia Keizo Asami , firstname.lastname@example.org|
Background: Pulse oxygen saturation (POS) is a great strategy for screening critical congenital heart disease. Nomograms for pre-ductal and post-ductal POS have been described, but several factors like skin color, ambient temperature, altitude, presence of anemia, and others can modify them. Therefore, the analysis of nomograms in a developing country can be useful to optimize the screening for critical congenital heart disease (CCHD).
Objectives: to describe and analyze results of nomograms derived from pulse oximetry saturations from newborns screened for critical congenital heart disease in a state in Northeast Brazil.
Methods: Asymptomatic newborns with gestational age equal or above 34 weeks were screened for critical congenital heart disease through physical examination and pulse oximetry. We divided them according to gender, Apgar, the time when the pulse oximetry was performed and gestational age. The results of pre and post ductal saturations were compared among these groups with non-parametric tests. Twenty health centers were included.
Results: 44647 newborns screened for critical congenital heart disease were analyzed. The mean for preductal saturation was 97.37% and for post-ductal saturation was 97.44%. Statistical differences were encountered between pre and postducal saturations in almost all groups. Preterm neonates had lower saturations when compared with term neonates (p<0.001).
Conclusion: Nomograms for pre and post-ductal saturations, and differences between them, were described in 44647 neonates from Northeast Brazil. These nomograms can be utilized to optimize screening criteria for critical congenital heart disease.
|Critical congenital heart disease, Oxygen saturation nomogram, Pulse oximetry screening universal screening|
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